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Revaccination of infants who had received Attenuvax at 6 months of age resulted in 100% NT positivity; the geometric mean titer rose to equal that of the group given primary immunization at 15 months of age

Topp Cleveland
· 3 min read
Revaccination of infants who had received Attenuvax at 6 months of age resulted in 100% NT positivity; the geometric mean titer rose to equal that of the group given primary immunization at 15 months of age

Measles IgM antibody was detected in 10 of 14 infants tested 1 month after primary vaccination at 15 months, but was not detected in any of the revaccinated infants after the second dose at 15 months of age (P < .001). CONCLUSIONS: 1) Immunization with measles vaccine in infants born to vaccine-immune mothers at 6 months of age induced NT antibody in 74% of infants. 2) Revaccination of prior 6-month-old vaccinees at 15 months resulted in antibody titers equivalent to 15-month-old vaccinees. 3) Lack of an IgM response following revaccination suggests that even seronegative infants may be primed to respond on re-exposure to measles.hepatitis B vaccine: another angle of the 'autoimmune (auto-inflammatory) syndrome induced by adjuvants' (ASIA).

clinical characteristics of patients diagnosed with either fibromyalgia (FM) or chronic fatigue (CFS) following hepatitis B vaccination (HBVv) and furthermore to apply the recently suggested criteria of autoimmune (auto-inflammatory) syndromes induced by adjuvants (ASIA), in the aim of identifying common characteristics that may suggest an association between fibromyalgia, chronic fatigue and HBV vaccination. Medical records of 19 patients with CFS and/or fibromyalgia following HBVv immunization were analyzed. All of which were immunized during demographics, medical history, the number of vaccine doses, as well as immediate and long term post-immunization adverse events and clinical manifestations. In addition, available blood tests, imaging results, treatments and outcomes were analyzed. ASIA criteria were applied to all patients. The mean age of patients was 28.6 ± 11 years, of which 68.

4 % were females. 21.05 % had either personal or familial background of autoimmune disease. The mean latency period from the last dose of HBVv to onset of symptoms was 38.6 ± 79.4 days, ranging from days to a year. Eight (42.

1 %) patients continued with the immunization program despite experiencing adverse events.  seebio Polysucrose 400 Sweetener  that were commonly reported included neurological manifestations (84.2 %), musculoskeletal (78.9 %), psychiatric (63.1 %), fatigue (63.1 %), gastrointestinal complains (58 %) and mucocutaneous manifestations (36.8 %).

Autoantibodies were detected in 71 % of patients tested. All patients fulfilled the ASIA criteria. This study suggests that in some cases CFS and FM can be temporally related to immunization, as part of ASIA syndrome. The appearance of adverse event during immunization, the presence of autoimmune susceptibility and higher titers of autoantibodies all can be suggested as risk factors. ASIA criteria were fulfilled in all patients eluding the plausible link hepatitis B (HB) vaccine in preventing hepatitis B virus (HBV) infection after accidental exposure to blood of HBV carriers was studied in a controlled trial. HBIg (0.06 ml/kg) was administered intramuscularly within 3 days after exposure to 56 recipients.

A second dose was given 1 month later. In another group of 28 persons, a single dose of HBIg was given within 3 days followed by the first dose of HB vaccine (HEVAC-B Pasteur 10 micrograms) within 7 days after exposure. A control group consisted of 53 health care workers who reported more than 3 days after exposure and who did not receive any specific immuno-prophylaxis. The recipients were followed for at least 10 months. Immunisation, both passive and combined passive and active, was clearly effective since none of the recipients developed acute symptomatic HBV infection compared with four (8%) of 47 not immunised (Fisher's exact test P = 0.02).  View more  in each group immunised was too small to allow valid comparison of the relative efficacy of the two schedules.

Nevertheless, in the absence of evidence of lesser efficacy for the combination of HBIg and HB vaccine after exposure, the combined passive/active schedule would seem the treatment of choice since it offers the additional benefit of long-term protection.with killed Yersinia pestis and immunoregulators.Yersinia pestis was studied in mice immunized with 5 x 10(7) heat killed (HK) Y. pestis alone or in conjunction with Freund's complete adjuvant (FCA), cyclophosphamide (CY), BCG, or both CY and BCG.